Oxidative pentose phosphate pathway and glucose anaplerosis support maintenance of mitochondrial NADPH pool under mitochondrial oxidative stress

Abstract Mitochondrial NADPH protects cells against mitochondrial oxidative stress by serving as an electron donor to antioxidant defense systems. However, due to technical challenges, it still remains unknown as to the pool size of mitochondrial NADPH, its dynamics, and NADPH/NADP+ ratio. Here, we...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Sun Jin Moon, Wentao Dong, Gregory N. Stephanopoulos, Hadley D. Sikes
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Wiley 2020-09-01
Saila:	Bioengineering & Translational Medicine
Gaiak:	hydrogen peroxide mitochondria NADPH NADPH metabolism NADPH sensor oxidative stress
Sarrera elektronikoa:	https://doi.org/10.1002/btm2.10184
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!