Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells

Robust, long-lasting immune responses are elicited by memory T cells that possess properties of stem cells, enabling them to persist long-term and to permanently replenish the effector pools. Thus, stem cell-like memory T (TSCM) cells are of key therapeutic value and efforts are underway to characte...

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Bibliografiske detaljer

Principais autores:	Godehard Scholz, Camilla Jandus, Lianjun Zhang, Camille Grandclément, Isabel C. Lopez-Mejia, Charlotte Soneson, Mauro Delorenzi, Lluis Fajas, Werner Held, Olivier Dormond, Pedro Romero
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2016-02-01
Serier:	EBioMedicine
Fag:	Human T cells T cell differentiation Adoptive cell transfer therapy Rapamycin
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2352396416300159
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