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Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response

Traumatic spinal cord injury (SCI) is untreatable and remains the leading cause of disability. Neuroprotection and recovery after SCI can be partially achieved by rapamycin (RAPA) treatment, an inhibitor of mTORC1, complex 1 of the mammalian target of rapamycin (mTOR) pathway. However, mechanisms re...

Täydet tiedot

Tallennettuna:
Päätekijät: Ingrid Vargova, Lucia Machova Urdzikova, Kristyna Karova, Barbora Smejkalova, Tolga Sursal, Veronika Cimermanova, Karolina Turnovcova, Chirag D. Gandhi, Meena Jhanwar-Uniyal, Pavla Jendelova
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2021-05-01
Sarja:Biomedicines
Aiheet:
spinal cord injury
mTOR
rapamycin
pp242
dual inhibition
autophagy
Linkit:https://www.mdpi.com/2227-9059/9/6/593
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