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Exploring the tolerable region for HiBiT tag insertion in the hepatitis B virus genome

ABSTRACT A cell culture system that allows the reproduction of the hepatitis B virus (HBV) life cycle is indispensable to exploring novel anti-HBV agents. To establish the screening system for anti-HBV agents, we exploited the high affinity and bright luminescence (HiBiT) tag and comprehensively exp...

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Principais autores: Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Masaaki Toyama, Masanori Isogawa, Tetsuro Shimakami, Takanobu Kato
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2024-10-01
coleção:mSphere
Assuntos:
HBV
preS1
luciferase
NTCP
primary hepatocyte
Acesso em linha:https://journals.asm.org/doi/10.1128/msphere.00518-24
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