Exploring the tolerable region for HiBiT tag insertion in the hepatitis B virus genome

ABSTRACT A cell culture system that allows the reproduction of the hepatitis B virus (HBV) life cycle is indispensable to exploring novel anti-HBV agents. To establish the screening system for anti-HBV agents, we exploited the high affinity and bright luminescence (HiBiT) tag and comprehensively exp...

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Autores principales:	Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Masaaki Toyama, Masanori Isogawa, Tetsuro Shimakami, Takanobu Kato
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2024-10-01
Colección:	mSphere
Materias:	HBV preS1 luciferase NTCP primary hepatocyte
Acceso en línea:	https://journals.asm.org/doi/10.1128/msphere.00518-24
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