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Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21<sup>WAF1/CIP1</sup> and p27<sup>KIP1</sup> in Cancer Cells

<i>Background and Objective</i>: Alterations in gene expressions are often due to epigenetic modifications that can have a significant influence on cancer development, growth, and progression. Lately, histone deacetylase inhibitors (HDACi) such as suberoylanilide hydroxamic acid (SAHA, or vorinostat...

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Príomhchruthaitheoirí: Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Periannan Rasappan, Appu Rathinavelu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2019-01-01
Sraith:Medicina
Ábhair:
Rochtain ar líne:https://www.mdpi.com/1010-660X/55/2/30
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