Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21^WAF1/CIP1 and p27^KIP1 in Cancer Cells

<i>Background and Objective</i>: Alterations in gene expressions are often due to epigenetic modifications that can have a significant influence on cancer development, growth, and progression. Lately, histone deacetylase inhibitors (HDACi) such as suberoylanilide hydroxamic acid (SAHA, or vorinostat...

Description complète

Détails bibliographiques

Auteurs principaux:	Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Periannan Rasappan, Appu Rathinavelu
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2019-01-01
Collection:	Medicina
Sujets:	SAHA RG7388 MDM2 p53 p21 cell cycle arrest cell death
Accès en ligne:	https://www.mdpi.com/1010-660X/55/2/30
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!