Pharmacological Responses of the G542X-CFTR to CFTR Modulators
Cystic fibrosis (CF) is a lethal hereditary disease caused by loss-of-function mutations of the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR). With the development of small-molecule CFTR modulators, including correctors that facilitate protein folding and expression and...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2022-06-01
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| Serier: | Frontiers in Molecular Biosciences |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.921680/full |
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