BRAFV600E/pTERT double mutated papillary thyroid cancers exhibit immune gene suppression

IntroductionBRAFV600E mutation (BRAFmut) is common in papillary thyroid cancer (PTC), and most patients have an excellent outcome. However, a TERT-promoter mutation (pTERTmut) in the presence of BRAFmut (BRAFmutpTERTmut) has been demonstrated to confer a more aggressive behavior to PTC. Lymphocytic...

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主要な著者:	Ana-Maria Sigarteu Chindris, Michael Rivera, Yaohua Ma, Asha Nair, Yi Liu, Xue Wang, Brian M. Necela, Jennifer M. Kachergus, John D. Casler, Christopher Brett, Ana M. Rivas Mejia, Victor J. Bernet, John A. Copland, Keith L. Knutson, E. Aubrey Thompson, Robert C. Smallridge
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2024-12-01
シリーズ:	Frontiers in Endocrinology
主題:	papillary thyroid cancer (PTC) BRAF mutation V600 E TERT promoter mutation (pTERT) immune genes lymphocytic infiltration
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1440722/full
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