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New and Effective Inhibitor of Class I HDACs, Eimbinostat, Reduces the Growth of Hematologic Cancer Cells and Triggers Apoptosis

<b>Background:</b> Histone deacetylases (HDACs) are critical epigenetic modulators involved in regulating various molecular mechanisms essential for cell development and growth. Alterations in HDAC activity have been linked to the progression of numerous cancers, including lymphoma. Over the past de...

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Huvudupphov: Pavel Spirin, Valeria Vedernikova, Tatsiana Volkava, Alexey Morozov, Alla Kleymenova, Anastasia Zemskaya, Lena Shyrokova, Yuri Porozov, Ksenia Glumakova, Timofey Lebedev, Maxim Kozlov, Vladimir Prassolov
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2025-03-01
Serie:Pharmaceutics
Ämnen:
epigenetic
HDACs
belinostat
lymphoma
leukemia
apoptosis
Länkar:https://www.mdpi.com/1999-4923/17/4/416
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