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Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS

Undruggability of RAS proteins has necessitated alternative strategies for the development of effective inhibitors. In this respect, phosphorylation has recently come into prominence as this reversible post-translational modification attenuates sensitivity of RAS towards RAF. As such, in this study,...

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Detaylı Bibliyografya
Asıl Yazarlar: Metehan Ilter, Ramazan Kasmer, Farzaneh Jalalypour, Canan Atilgan, Ozan Topcu, Nihal Karakas, Ozge Sensoy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications Ltd 2022-12-01
Seri Bilgileri:eLife
Konular:
Online Erişim:https://elifesciences.org/articles/79747
Etiketler: Etiketle
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