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Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa

The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-kDa protein whose structure and proper locali...

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Principais autores: Charlotte Lombardi, James Tolchard, Stephanie Bouillot, Luca Signor, Caroline Gebus, David Liebl, Daphna Fenel, Jean-Marie Teulon, Juliane Brock, Birgit Habenstein, Jean-Luc Pellequer, Eric Faudry, Antoine Loquet, Ina Attrée, Andréa Dessen, Viviana Job
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-03-01
coleção:Frontiers in Microbiology
Assuntos:
type III secretion system
Pseudomonas aeruginosa
T3SS needle
structure
virulence
immunofluorescence microscopy
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2019.00573/full
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