Directed evolution of phage Romulus in biofilm-embedded Staphylococcus aureus: mutations in baseplate proteins enhanced its antibiofilm activity

The ability of Staphylococcus aureus to form biofilm and the emergence of multidrug-resistant strains make staphylococcal infections often chronic and difficult to treat. To face these challenges, alternative or adjunct strategies to antibiotics are urgently required. In this context, phage therapy...

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Detalhes bibliográficos

Principais autores:	Claudia Campobasso, Pauline Henderix, Ekaterina Jalomo-Khayrova, Sara Bolognini, Gert Bange, Rob Lavigne, Arianna Tavanti, Jeroen Wagemans, Mariagrazia Di Luca
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-06-01
coleção:	Biofilm
Assuntos:	Staphylococcus aureus Biofilm Bacteriophages Directed evolution Baseplate
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S259020752600002X
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