TRIM5 alpha drives SIVsmm evolution in rhesus macaques.
The antagonistic interaction with host restriction proteins is a major driver of evolutionary change for viruses. We previously reported that polymorphisms of the TRIM5α B30.2/SPRY domain impacted the level of SIVsmm viremia in rhesus macaques. Viremia in macaques homozygous for the non-restrictive...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2013-01-01
|
| Schriftenreihe: | PLoS Pathogens |
| Online-Zugang: | http://europepmc.org/articles/PMC3749954?pdf=render |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|