TRIM5 alpha drives SIVsmm evolution in rhesus macaques.
The antagonistic interaction with host restriction proteins is a major driver of evolutionary change for viruses. We previously reported that polymorphisms of the TRIM5α B30.2/SPRY domain impacted the level of SIVsmm viremia in rhesus macaques. Viremia in macaques homozygous for the non-restrictive...
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| Principais autores: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2013-01-01
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| Serija: | PLoS Pathogens |
| Online dostop: | http://europepmc.org/articles/PMC3749954?pdf=render |
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