Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus

Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppression caused by the virus and the genetic diversity in PRRSV, no virus-tar...

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Autori principali:	Haotian Yang, Meiqi Sun, He Qiu, Huiling Xu, Zhuofan Deng, Han Gu, Nan Wang, Liuyang Du, Fushan Shi, Jiyong Zhou, Fang He
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-07-01
Serie:	Journal of Nanobiotechnology
Soggetti:	PRRSV Antiviral peptides Broad neutralization Nanobody Receptor binding domain
Accesso online:	https://doi.org/10.1186/s12951-024-02662-7
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