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Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus

Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppression caused by the virus and the genetic diversity in PRRSV, no virus-tar...

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Principais autores: Haotian Yang, Meiqi Sun, He Qiu, Huiling Xu, Zhuofan Deng, Han Gu, Nan Wang, Liuyang Du, Fushan Shi, Jiyong Zhou, Fang He
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-07-01
coleção:Journal of Nanobiotechnology
Assuntos:
PRRSV
Antiviral peptides
Broad neutralization
Nanobody
Receptor binding domain
Acesso em linha:https://doi.org/10.1186/s12951-024-02662-7
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