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A comparative assessment of the antidepressant efficacy of ketamine, psilocybin, and fluoxetine in a chronic stress model

Abstract Depression is a debilitating mental disorder affecting millions worldwide, yet current pharmacological treatments, such as selective serotonin reuptake inhibitors (SSRIs), often exhibit delayed onset and limited efficacy. The chronic social defeat (CSD) stress model in mice is a well-establ...

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Autori principali: Małgorzata Domżalska, Joanna Kwiatkowska, Iwona Cichoń, Ewa Sokołowska
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-11-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-29642-7
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