A comparative assessment of the antidepressant efficacy of ketamine, psilocybin, and fluoxetine in a chronic stress model

Abstract Depression is a debilitating mental disorder affecting millions worldwide, yet current pharmacological treatments, such as selective serotonin reuptake inhibitors (SSRIs), often exhibit delayed onset and limited efficacy. The chronic social defeat (CSD) stress model in mice is a well-establ...

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Bibliografische gegevens

Hoofdauteurs:	Małgorzata Domżalska, Joanna Kwiatkowska, Iwona Cichoń, Ewa Sokołowska
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Portfolio 2025-11-01
Reeks:	Scientific Reports
Onderwerpen:	Chronic social defeat Treatment-resistant depression Antidepressant efficacy Ketamine Psilocybin Fluoxetine
Online toegang:	https://doi.org/10.1038/s41598-025-29642-7
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