Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancer

Abstract Peripheral blood (PB) is a source of tumor-infiltrating tumor-reactive T cells (TR-T). Circulating TR-Ts (cTR-T) in PB are expected to contribute to the efficacy of immune checkpoint inhibitors (ICIs), but their phenotype remains poorly understood. Here we analyse paired tumor-infiltrating...

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Үндсэн зохиолчид:	Katsuhiro Ito, Kei Iida, Tomoko Hirano, Merrin Man Long Leong, Kenji Morii, Toshi Menju, Hiroshi Date, Hiroaki Ozasa, Hironori Yoshida, Toyohiro Hirai, Shusuke Kawashima, Kazuhiro Aoyama, Yuka Saeki, Takashi Inozume, Takashi Kobayashi, Kenji Chamoto, Tomonori Yaguchi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2026-02-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-026-69680-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!