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Phenotype of circulating tumor-reactive T cells predicts immune checkpoint inhibitor response in non-small cell lung cancer

Abstract Peripheral blood (PB) is a source of tumor-infiltrating tumor-reactive T cells (TR-T). Circulating TR-Ts (cTR-T) in PB are expected to contribute to the efficacy of immune checkpoint inhibitors (ICIs), but their phenotype remains poorly understood. Here we analyse paired tumor-infiltrating...

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Wedi'i Gadw mewn:
Prif Awduron: Katsuhiro Ito, Kei Iida, Tomoko Hirano, Merrin Man Long Leong, Kenji Morii, Toshi Menju, Hiroshi Date, Hiroaki Ozasa, Hironori Yoshida, Toyohiro Hirai, Shusuke Kawashima, Kazuhiro Aoyama, Yuka Saeki, Takashi Inozume, Takashi Kobayashi, Kenji Chamoto, Tomonori Yaguchi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2026-02-01
Cyfres:Nature Communications
Mynediad Ar-lein:https://doi.org/10.1038/s41467-026-69680-x
Tagiau: Ychwanegu Tag
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