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A proximity-labeling-based approach to directly detect mRNA delivery to specific subcellular locations

Messenger RNA (mRNA) therapeutics show considerable promise but face delivery challenges, as effective cytosolic entry and subsequent translation are normally limited by endosomal entrapment. While various approaches have been used to investigate determinants of effective RNA delivery, these methods...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Alfredo D. Smart, Merryn E. Hughes, Angela Downie Ruiz Velasco, Naoto Hori, Snow Stolnik, Catherine L. Jopling
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2025-09-01
Rangatū:Molecular Therapy: Nucleic Acids
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2162253125001568
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