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Insulin production in the retina drives autocrine signalling and metabolism reprogramming of the ARPE-19, a retinal pigment epithelium cellular model

Abstract The retinal pigment epithelium (RPE) plays a pivotal role in retinal homeostasis and energy metabolism. A recent study demonstrates that RPE cells release insulin in response to photoreceptor outer segment (POS) phagocytosis and starvation conditions. However, the downstream signalling path...

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Detaylı Bibliyografya
Asıl Yazarlar: Alessandra Puddu, Matilde Balbi, Silvia Ravera, Isabella Panfoli, Davide Maggi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer 2026-05-01
Seri Bilgileri:Cellular and Molecular Life Sciences
Konular:
Online Erişim:https://doi.org/10.1007/s00018-026-06222-0
Etiketler: Etiketle
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