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WNT signaling contributes to the extrahepatic bile duct proliferative response to obstruction in mice

Biliary obstruction and cholangiocyte hyperproliferation are important features of cholangiopathies affecting the large extrahepatic bile duct (EHBD). The mechanisms underlying obstruction-induced cholangiocyte proliferation in the EHBD remain poorly understood. Developmental pathways, including WNT...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ashley N. Calder, Mirabelle Q. Peter, John W. Tobias, Nureen H. Mohamad Zaki, Theresa M. Keeley, Timothy L. Frankel, Linda C. Samuelson, Nataliya Razumilava
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Clinical investigation 2025-01-01
Цуврал:JCI Insight
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1172/jci.insight.181857
Шошгууд: Шошго нэмэх
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