Transfer learning with false negative control improves polygenic risk prediction.
Polygenic risk score (PRS) is a quantity that aggregates the effects of variants across the genome and estimates an individual's genetic predisposition for a given trait. PRS analysis typically contains two input data sets: base data for effect size estimation and target data for individual-level pr...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2023-11-01
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| Серии: | PLoS Genetics |
| Online-ссылка: | https://doi.org/10.1371/journal.pgen.1010597 |
| Метки: |
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