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Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2

Abstract The cellular membrane in male meiotic germ cells contains a unique class of phospholipids and sphingolipids that is required for male reproduction. Here, we show that a conserved membrane fluidity sensor, AdipoR2, regulates the meiosis-specific lipidome in mouse testes by promoting the synt...

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Bibliografski detalji
Glavni autori: Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanović, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernández-Hernández, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2024-03-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-024-46718-6
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