Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats

Cell-based transplantation strategies possess great potential for spinal cord injury (SCI) repair. Basic fibroblast growth factor (bFGF) has been reported to have multiple neuro-promoting effects on developing and adult nervous system of mammals and considered a promising therapy for nerve injury fo...

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Автори:	Sipin Zhu, Yibo Ying, Yan He, Xingxing Zhong, Jiahui Ye, Zhiyang Huang, Min Chen, Qiuji Wu, Yifan Zhang, Ziyue Xiang, Yurong Tu, Weiyang Ying, Jian Xiao, Xiaokun Li, Qingsong Ye, Zhouguang Wang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	KeAi Communications Co., Ltd. 2021-08-01
Серія:	Bioactive Materials
Предмети:	Spinal cord injury Adeno-associated virus Basic fibroblast growth factor Dental pulp stem cell Vascular regulation Hypoxic microenvironment
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2452199X21000347
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