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Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy

Protecting the death of nerve cells is an essential tactic for spinal cord injury (SCI) repair. Recent studies show that nerve growth factors can reduce the death of nerve cells and promote the healing of nerve injury. To investigate the conducive effect of fibroblast growth factor 21 (FGF21) on SCI...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sipin Zhu, Yibo Ying, Lin Ye, Weiyang Ying, Jiahui Ye, Qiuji Wu, Min Chen, Hui Zhu, Xiaoyang Li, Haicheng Dou, Huazi Xu, Zhouguang Wang, Jiake Xu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-01-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
spinal cord injury
fibroblast growth factor 21
autophagy
nerve regeneration
fibrotic scar
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2020.628369/full
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