Structural insights into global mutations in the ligand-binding domain of VAR2CSA and its implications on placental malaria vaccine

Placental malaria is a public health burden particularly in Africa as it causes severe symptoms and results in stillbirths or maternal deaths. Plasmodium falciparum protein VAR2CSA drives placental malaria (PM) in pregnant women by adhering to chondroitin sulfate A (CSA) on the placenta. VAR2CSA is...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Jasmita Gill, Soumyananda Chakraborti, Praveen Bharti, Amit Sharma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-11-01
Colecção:	International Journal of Infectious Diseases
Assuntos:	Placental malaria VAR2CSA Placental malaria vaccine Field isolates, Structural mapping
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1201971221006871
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!