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MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin

Abstract Background Diabetes is a leading cause of mortality and morbidity across the world. Over 50% of deaths among diabetic patients are caused by cardiovascular diseases. Cardiac diastolic dysfunction is one of the key early signs of diabetic cardiomyopathy, which often occurs before systolic dy...

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Main Authors: Beibei Dai, Huaping Li, Jiahui Fan, Yanru Zhao, Zhongwei Yin, Xiang Nie, Dao Wen Wang, Chen Chen
Format: Artigo
Language:Inglês
Published: BMC 2018-09-01
Series:Cardiovascular Diabetology
Subjects:
miRNA
Diabetic cardiomyopathy
Diastolic dysfunction
ROS
NO
Online Access:http://link.springer.com/article/10.1186/s12933-018-0767-z
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