A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a

Summary: It has been unclear whether the elevated levels of the circulating miR-320a in patients with coronary artery disease is due to environmental influence or genetic basis. By recombinant adeno-associated virus (rAAV)-mediated loss- and gain-of-function studies in the mouse liver, we revealed t...

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Detalhes bibliográficos

Principais autores:	Zhongwei Yin, Yanru Zhao, Hengzhi Du, Xiang Nie, Huaping Li, Jiahui Fan, Mengying He, Beibei Dai, Xudong Zhang, Shuai Yuan, Zheng Wen, Chen Chen, Dao Wen Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-12-01
coleção:	iScience
Assuntos:	Human Metabolism Genetics Genomic
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2589004220309858
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