Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)

The purpose of the study was to develop an SNEDDS to improve the solubility and bioavailability of pitavastatin. The solubility of pitavastatin in different oils, surfactants, and co-surfactants was determined and a pseudo-ternary phase diagram was constructed. The SNEDDS was characterized by zeta-s...

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Главные авторы:	Mehran Ashfaq, Shahid Shah, Akhtar Rasul, Muhammad Hanif, Hafeez Ullah Khan, Ahmed Khames, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Muhammad Yasir Ali, Mohammad A. S. Abourehab, Safirah Maheen, Omeira Iqbal, Ghulam Abbas, Amani M. El Sisi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-02-01
Серии:	Pharmaceutics
Предметы:	nanoemulsion pitavastatin drug release cytotoxicity pharmacokinetics
Online-ссылка:	https://www.mdpi.com/1999-4923/14/3/482
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