Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction

Abstract Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO). This study aims to clarify the time-dependent molecular pathways by which TMAO mediates endothelial dysfunction thr...

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Bibliografiske detaljer

Principais autores:	Meyammai Shanmugham, Arun George Devasia, Yu Ling Chin, Kang Hao Cheong, Eng Shi Ong, Sophie Bellanger, Adaikalavan Ramasamy, Chen Huei Leo
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2023-11-01
Serier:	Scientific Reports
Online adgang:	https://doi.org/10.1038/s41598-023-46820-7
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