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Gut-Derived Metabolite, Trimethylamine-N-oxide (TMAO) in Cardio-Metabolic Diseases: Detection, Mechanism, and Potential Therapeutics

Trimethylamine N-oxide (TMAO) is a biologically active gut microbiome-derived dietary metabolite. Recent studies have shown that high circulating plasma TMAO levels are closely associated with diseases such as atherosclerosis and hypertension, and metabolic disorders such as diabetes and hyperlipide...

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Principais autores: Meyammai Shanmugham, Sophie Bellanger, Chen Huei Leo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Pharmaceuticals
Fag:
TMAO
endothelial dysfunction
cardio-metabolic diseases
inflammation
oxidative stress
Online adgang:https://www.mdpi.com/1424-8247/16/4/504
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