CGRP-dependent sensitization of PKC-δ positive neurons in central amygdala mediates chronic migraine
Abstract Background To investigate specific brain regions and neural circuits that are responsible for migraine chronification. Methods We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2022-12-01
|
| Collection: | The Journal of Headache and Pain |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1186/s10194-022-01531-8 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|