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Selective Inhibition of Cardiac Late Na<sup>+</sup> Current Is Based on Fast Offset Kinetics of the Inhibitor

The present study was designed to test the hypothesis that the selectivity of blocking the late Na<sup>+</sup> current (I<sub>NaL</sub>) over the peak Na<sup>+</sup> current (I<sub>NaP</sub>) is related to the fast offset kinetics of the Na<sup>+</sup> channel inhibitor. Therefore, the effects of 1...

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Autors principals: Muhammad Naveed, Aiman Saleh A. Mohammed, Leila Topal, Zsigmond Máté Kovács, Csaba Dienes, József Ovári, Norbert Szentandrássy, János Magyar, Tamás Bányász, János Prorok, Norbert Jost, László Virág, István Baczkó, András Varró, Péter P. Nánási, Balázs Horváth
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-08-01
Col·lecció:Biomedicines
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Accés en línia:https://www.mdpi.com/2227-9059/11/9/2383
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