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Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro

Abstract Background HIV-1 produces defective mutants in the process of reproduction. The significance of the mutants has not been well investigated. Methods The plasmids of wild type (HIV-1NL4–3) and Env-defective (HIV-1SG3 ΔEnv) HIV-1 were co-transfected into HEK293T cells. The progeny virus was co...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huamian Wei, Danwei Yu, Xiuzhu Geng, Yuxian He
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2020-08-01
Saila:BMC Infectious Diseases
Gaiak:
Sarrera elektronikoa:http://link.springer.com/article/10.1186/s12879-020-05288-w
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