Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro
Abstract Background HIV-1 produces defective mutants in the process of reproduction. The significance of the mutants has not been well investigated. Methods The plasmids of wild type (HIV-1NL4–3) and Env-defective (HIV-1SG3 ΔEnv) HIV-1 were co-transfected into HEK293T cells. The progeny virus was co...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2020-08-01
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| Serie: | BMC Infectious Diseases |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s12879-020-05288-w |
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