Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic target.

The last step of cysteine biosynthesis in bacteria and plants is catalyzed by O-acetylserine sulfhydrylase. In bacteria, two isozymes, O-acetylserine sulfhydrylase-A and O-acetylserine sulfhydrylase-B, have been identified that share similar binding sites, although the respective specific functions...

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Bibliografske podrobnosti

Principais autores:	Francesca Spyrakis, Ratna Singh, Pietro Cozzini, Barbara Campanini, Enea Salsi, Paolo Felici, Samanta Raboni, Paolo Benedetti, Gabriele Cruciani, Glen E Kellogg, Paul F Cook, Andrea Mozzarelli
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2013-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC3805590?pdf=render
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