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Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic glycolysis

Abstract Background and purpose The aim of this study is to decipher the underlying mechanisms of CCAAT/enhancer‐binding protein delta (CEBPD)‐enhanced glycolysis as well as the biological significance of CEBPD and MYC coamplification in urothelial carcinoma (UC). Methods In vitro analyses were cond...

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Principais autores: Ti‐Chun Chan, Yi‐Ting Chen, Kien Thiam Tan, Chia‐Ling Wu, Wen‐Jeng Wu, Wei‐Ming Li, Ju‐Ming Wang, Yow‐Ling Shiue, Chien‐Feng Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2021-12-01
Serier:Clinical and Translational Medicine
Fag:
CEBPD
coamplification
glycolysis
MYC
urothelial carcinoma
Online adgang:https://doi.org/10.1002/ctm2.674
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