Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic glycolysis

Abstract Background and purpose The aim of this study is to decipher the underlying mechanisms of CCAAT/enhancer‐binding protein delta (CEBPD)‐enhanced glycolysis as well as the biological significance of CEBPD and MYC coamplification in urothelial carcinoma (UC). Methods In vitro analyses were cond...

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Autori principali:	Ti‐Chun Chan, Yi‐Ting Chen, Kien Thiam Tan, Chia‐Ling Wu, Wen‐Jeng Wu, Wei‐Ming Li, Ju‐Ming Wang, Yow‐Ling Shiue, Chien‐Feng Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2021-12-01
Serie:	Clinical and Translational Medicine
Soggetti:	CEBPD coamplification glycolysis MYC urothelial carcinoma
Accesso online:	https://doi.org/10.1002/ctm2.674
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