Age and onset timing of Raynaud’s phenomenon and first non-Raynaud symptom as prognostic factors in systemic sclerosis: a retrospective analysis from the Italian national multicenter Systemic Sclerosis Progression INvestiGation registry of the Italian Society for Rheumatology (SPRING-SIR)
Background: The sequence and temporal relationship between Raynaud’s phenomenon (RP) and the first non-Raynaud’s sign/symptom (NRP) in systemic sclerosis (SSc) have been partially investigated. Objectives: To evaluate whether the mode and ages of clinical onset are associated with disease endotype a...
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| Natura: | Artigo |
| Lingua: | Inglês |
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SAGE Publishing
2026-02-01
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| Serie: | Therapeutic Advances in Musculoskeletal Disease |
| Accesso online: | https://doi.org/10.1177/1759720X251410243 |
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