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Antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection downregulates the levels of interferon-gamma/lambdas in porcine alveolar macrophages in vitro

Fc gamma receptor-mediated antibody-dependent enhancement (ADE) can promote virus invasion of target cells, sometimes exacerbating the severity of the disease. ADE may be an enormous hurdle to developing efficacious vaccines for certain human and animal viruses. ADE of porcine reproductive and respi...

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Principais autores: Liujun Zhang, Xing Feng, Huandi Wang, Shaojun He, Hongjie Fan, Deyi Liu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Veterinary Science
Fag:
PRRSV-ADE
IFN-γ
IFN-λs
TGF-β1
PAMs
Online adgang:https://www.frontiersin.org/articles/10.3389/fvets.2023.1150430/full
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