Antibody-Dependent Enhancement of Porcine Reproductive and Respiratory Syndrome Virus Infection Antagonizes the Secretion of Type I Interferons in Porcine Alveolar Macrophages by Interfering with the Retinoic Acid-Inducible Gene I/Melanoma Differentiation-Associated Gene 5 Pathway via Fc Gamma Receptor I

Type I interferons (IFNs), mainly IFN-α and IFN-β, play an essential role in defending against viral invasion by inducing the host’s innate antiviral response. Porcine reproductive and respiratory syndrome virus (PRRSV) is known to impair the IFN responses of infected hosts through the antibody-depe...

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Principais autores:	Liujun Zhang, Aiyang Wang, Weizhen Chen, Xing Feng, Bo Wang, Shaojun He, Hongjie Fan
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2025-09-01
Serija:	Viruses
Teme:	PRRSV ADE FcγRI RIG-I MDA5 Type I IFNs
Online dostop:	https://www.mdpi.com/1999-4915/17/9/1277
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