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Regulating Lars2 in mitochondria: A potential Alzheimer's therapy by inhibiting tau phosphorylation

Driven by the scarcity of effective treatment options in clinical settings, the present study aimed to identify a new potential target for Alzheimer's disease (AD) treatment. We focused on Lars2, an enzyme synthesizing mitochondrial leucyl-tRNA, and its role in maintaining mitochondrial function. Bi...

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Detalles Bibliográficos
Principais autores: Wenqi Qian, Lin Yuan, Weishan Zhuge, Liuqing Gu, Yutian Chen, Qichuan Zhuge, Haoqi Ni, Xinhuang Lv
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-07-01
Series:Neurotherapeutics
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S1878747924000394
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