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Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

Neuronal aging and neurodegenerative diseases are accompanied by proteostasis collapse, while the cellular factors that trigger it have not been identified. Impaired mitochondrial transport in the axon is another feature of aging and neurodegenerative diseases. Using Drosophila, we found that geneti...

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Bibliografische Detailangaben
Hauptverfasser: Kanako Shinno, Yuri Miura, Koichi M Iijima, Emiko Suzuki, Kanae Ando
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2026-01-01
Schriftenreihe:eLife
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Online-Zugang:https://elifesciences.org/articles/95576
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