Interaction between <i>M. tuberculosis</i> Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB

Tuberculosis (TB) remains a major public health threat globally, especially in sub-Saharan Africa. Both human and <i>Mycobacterium tuberculosis</i> (MTBC) genetic variation affect TB outcomes, but few studies have examined if and how the two genomes interact to affect disease. We hypothesize that lo...

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Autors principals:	Michael L. McHenry, Eddie M. Wampande, Moses L. Joloba, LaShaunda L. Malone, Harriet Mayanja-Kizza, William S. Bush, W. Henry Boom, Scott M. Williams, Catherine M. Stein
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-11-01
Col·lecció:	Pathogens
Matèries:	tuberculosis severity <i>M. tuberculosis</i> population genetics lineage-based GWAS <i>M. tuberculosis</i>–human coevolution
Accés en línia:	https://www.mdpi.com/2076-0817/10/11/1487
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