Vaccinia Virus Ankyrin-Repeat/F-Box Protein Targets Interferon-Induced IFITs for Proteasomal Degradation
Summary: IFITs are interferon-induced proteins that can bind 5′-triphosphate or ribose-unmethylated capped ends of mRNA to inhibit translation. Although some viruses avoid IFITs by synthesizing RNAs with eukaryotic-like caps, no viral proteins were known to antagonize IFITs. We show that the N- and...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2019-10-01
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| Серии: | Cell Reports |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2211124719312276 |
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