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Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics

Abstract The glutathione (GSH) redox system plays a central role in maintaining cellular homeostasis, but its dysregulation in cancer contributes to tumor progression, therapy resistance, and metabolic adaptation. Elevated intracellular GSH levels represent both a barrier to conventional therapies a...

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Bibliographic Details
Main Author: Rana R. El Sadda
Format: Artigo
Language:Inglês
Published: Springer 2026-02-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-026-04456-9
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