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Glutathione responsive nanomedicine leverages tumor redox imbalance for targeted cancer theranostics

Abstract The glutathione (GSH) redox system plays a central role in maintaining cellular homeostasis, but its dysregulation in cancer contributes to tumor progression, therapy resistance, and metabolic adaptation. Elevated intracellular GSH levels represent both a barrier to conventional therapies a...

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Autor principal: Rana R. El Sadda
Format: Artigo
Idioma:Inglês
Publicat: Springer 2026-02-01
Col·lecció:Discover Oncology
Matèries:
Accés en línia:https://doi.org/10.1007/s12672-026-04456-9
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